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Hepatitis B Therapeutics in Major Developed Industrial and Market studiess to 2021 - Increasing Number of Migrants from

New update "Hepatitis B Therapeutics in Major Developed Markets to 2021 - Increasing Number of Migrants from High-Prevalence Regions to Drive Market G
Rmoz Ganesh VP | 08.11.2016

"Hepatitis B Therapeutics in Major Developed Markets to 2021 - Increasing Number of Migrants from High-Prevalence Regions to Drive Market Growth" The Report covers current Market Trends, Analysis, Forecast, Review, Share, Size, Growth, Effect.


Description-


Hepatitis B is an infectious liver disease caused by the Hepatitis B Virus (HBV) and characterized by acute or chronic inflammation of the liver. Despite its status as a vaccine-preventable disease, it remains a serious global health concern. Incidence tends to be higher in countries with a significant number of migrants from medium and high-prevalence countries. Approximately 350 million people worldwide are infected with chronic hepatitis B, which causes significant morbidity and mortality. Around 780,000 patients die from hepatitis B each year, of which 650,000 deaths are due to complications such as cirrhosis and liver cancer. Despite this, diagnosis and treatment rates are poor, stemming from its asymptomatic nature.


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Globally, the hepatitis B therapeutics market is served moderately well by the available products, of which Baraclude and Viread are the most frequently prescribed. However, both have received black-box warnings from the US Food and Drug Administration (FDA), meaning that the market has a high level of unmet need.

Scope

  • The current hepatitis B market contains mainly nucleoside analog reverse transcriptase inhibitors, nucleotide analogs, and interferons.

  • Will these drugs continue to dominate hepatitis B treatment?

  • With 81 active pipeline molecules, most of the investigational drug candidates are small molecules and vaccines, comprising 64% of the pipeline.

  • What are the most prominent small molecules and vaccines in the pipeline?

  • Do the pipeline molecules offer advantages over commercially proven mechanisms?

  • Analysis of clinical trials since 2006 has identified a high rate of attrition in hepatitis B products.

  • How do failure rates vary by product stage of development, molecule type, and mechanism of action?

  • How do other factors such as average trial duration and trial size influence the costs and risks associated with product development?

  • Over the 2014


Table of Contents

1 Table of Contents 5
1.1 List of Tables 7
1.2 List of Figures 8

2 Introduction 9
2.1 Classification 9
2.2 Pathophysiology 9
2.3 Etiology 11
2.4 Symptoms 12
2.5 Diagnosis 12
2.6 Epidemiology 13

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About the tenderer: Rmoz Ganesh VP

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